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Discoid Lupus Erythematosus of the Lip- A Case Study

JOURNAL:MAZEDAN INTERNATIONAL JOURNAL OF MEDICAL RESEARCH

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1. Gyan Prasad Bajgai, Pema Yangzom, Tshering Dema 15 Nov 2021 na 35 0
Abstract

Discoid lupus erythematosus (DLE) is the commonest type of cutaneous lupus erythematosus that usually presents with involvement of oral mucosa and skin. Oral mucosal lesions of DLE are usually found in along with skin lesions. Discoid lupus erythematosus is an auto-immune disease commonly affecting the areas of skin exposed to the sun. Patients with DLE have increased levels of plasma-cytoid dendritic cells ?derived interferon??, which mediates both loss of immune tolerance to self?antigens and exaggerate inflammatory state. Timely diagnosis of mucosal DEL can protect from complications like squamous cell carcinoma (SCC), however it requires an advanced index of suspicion among patients having such lesions. Discoid lesions of the lip usually present as red and/or white plaques, with striations and/or telangiectasia. Photosensitivity and the long?standing immune?mediated chronic inflammation are a trigger for cancerous transformation in DLE. Early and timely diagnosis is important in management of DLE.

Keywords

Discoid lupus erythematosus, Lip, Woman, Chronic, Auto-immune

References

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    [2]           CRISPIAN SCULLY; ORAL & MAXILLOFACIAL MEDICINE TBODATTE.

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    [5]           Molomo EM, Bouckaert M, Khammissa RA, Motswaledi HM, Lemmer J, Feller L. Discoid lupus erythematosus-related squamous cell carcinoma of the lip in an HIV-seropositive black male. J Cancer Res Ther. 2015;11(4):1036.